Electrospinning
Electrospinning is a method of fabricating continuous fibers with nanoscale diameters of tens to hundreds of nanometers by applying electric fields to liquid polymers.
When electric fields are applied to polymeric droplets attached to the capillary tip, an electric charge is induced in the polymer.
This generates energy against the surface tension, and the surface of the solution is transformed into a cone shape called a “Taylor cone“.
If the electric field strength is greater than the surface tension, fibers are released from the tip of the Taylor cone.
Electrospinning technology has the following advantages: Spinning is possible at room temperature and it is easy to control the surface structure and hybridization. Most polymers can be used.
ST1 Co., Ltd. uses electrospinning technology to fabricate nanofiber membranes (nanometer-thick membrane in 3D form where nanofibers are layered like a network) with characteristics similar to the ECM (extracellular matrix) in the human body. In addition, we are expanding our efforts in R&D to various fields, including various types of scaffolds, nano membranes, and biochips that are inserted into the human body for the purposes of tissue, organ, and cell restoration and regeneration, as well as for treatments.
ST1’s technology
ST1 has secured a top class DWES process system with its own technology.
We also provide outstanding quality nanofibers with uniform fiber diameter and high porosity compared to those of other companies. We own production technologies utilizing various fibers (polymer, cell, hydrogel, etc.) and biomaterials (collagen, gelatin, PDMS, etc.).
Technology application and expansion fields
Biotech equipment
- 3D cell culture
- In vitro organ mimicking tissue (ex: bladder cancer model, prostate cancer model, brain cancer model, etc.)
- We overcome the limitations of 2D cell culture by providing an environment similar to the human body.
- As replacements for animal testing, costs can be remarkably reduced.
- You can use various materials through natural polymers (collagen, gelatin, chitosan) other than synthetic polymers.
- We are developing wound dressings / hemostatics / a GBR membrane / artificial skin.
- Drug screening can be done or drug effects can be predicted at the onset of diseases.
Regenerative medical devices
- Periodontal tissue regeneration (tooth regeneration, periodontal ligament regeneration, etc.)
- Tissue regeneration (ligament regeneration, cartilage regeneration, etc.)
- Tissue mimmics/organoids
- We regenerate tissues not as medicine for stem cell injection but by controlling the activity of existing pulp stem cells.
- We develop revolutionary tissue regenerative medicines that lower dependence on prosthetic replacements.
- We develop low-cost, highly efficient biodegradable regenerative scaffolds that deliver drugs or regenerate tissue.
- We develop tissue mimics/organoids for drug screening and to suggest patient-customized treatment options .
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